Several years ago, protease inhibitors were the Great White Hope of AIDS therapy. These drugs work by inhibiting the enzyme protease, which is crucial to HIV’s ability to reproduce.
Prednisolone is the most commonly prescribed corticosteroid, and its range of side-effects is awesome. GASP, the UK-based Group Action into Steroid Prescribing, polled its 15,000 members and found that 70 per cent of patients suffered weight gain,