What Doctors Don't Tell YouOnce upon a time there were arthritis drugs known as NSAIDs (non-steroidal anti-inflammatory drugs), but they caused gastrointestinal problems, such as ulcers.
COX-2 AGAIN: Sorry, we haven’t finished with you yet
For years, non-specific anti-inflammatory drugs such as aspirin and paracetamol (acetaminophen) were the medications of choice for joint pain. But NSAIDs quickly became COX-2 inhibitors associated with adverse gastrointestinal effects such as peptic...
Which drugs are COX-2 inhibitors? All NSAIDs, even those not classed specifically as COX-2 inhibitors, can act to inhibit COX-2 in the body (J Rheumatol, 1998; 25: 2298-302; FASEB J, 1998; 12: 1063-73).
The COX (cyclooxygenase)-2 inhibitors, also known as ‘selective non-steroidal anti-inflammatory drugs’ (NSAIDs), have long been touted as being safer for your stomach than painkillers such as aspirin and other NSAIDs. Indeed, they were designed to...
COX-2: Still bleeding after all these years
In the heady world of the pharmaceutical industry, the most profitable industry in the world - where world sales doubled in the last five years - the pressure is always intense to develop new product.
Another anti-inflammatory bites the dust. Another COX-2 inhibitor has been shot down by the FDA. Having spent the last two months reviewing the safety of the COX-2-selective non-steroidal anti-inflammatory drugs (NSAIDs), the US regulatory agency...
DRUG ALERTS: New warnings
Vioxx (rofecoxib) is the first of a new kind of analgesic to be licensed in the UK. It employs a pioneering technology called COX-2 (selective cyclo oygenase 2 inhibitors), which is supposed to o ...
