For years, non-specific anti-inflammatory drugs such as aspirin and paracetamol (acetaminophen) were the medications of choice for joint pain. But NSAIDs quickly became COX-2 inhibitors associated with adverse gastrointestinal effects such as peptic...
Some observers believe that arthritis may be the result of abnormal glucosamine metabolism. In the body, glucosamine works by stopping the breakdown of proteoglycans
Which drugs are COX-2 inhibitors? All NSAIDs, even those not classed specifically as COX-2 inhibitors, can act to inhibit COX-2 in the body (J Rheumatol, 1998; 25: 2298-302; FASEB J, 1998; 12: 1063-73).
What Doctors Don't Tell You