Those who have been diagnosed with this condition, also known as “thalamic syndrome”, have usually suffered injury in the thalamus, the right hand side of the brain, following a stroke. This injury leads to a constant and unrelenting pain that has been described as burning, aching, or pricking in nature. The conventional route to managing this condition is with anti-depressants but what if even those don’t work? Are there any effective alternative painkillers that can relieve the symptoms? Omega-3 and omega-6 oils can stimulate the pathways which result in the production of two anti-inflammatory prostaglandins PG1 and PG3. These fatty acids have helped a reader deal with post-herpetic neuralgia, which, according to him, sounds similar to CPSP. Sugar and other simple carbohydrates should also be eliminated as they cause the release of high levels of insulin, which blocks the synthesis of the anti-inflammatory prostaglandins. Other alternative pain-relief therapies recommended by readers include homeopathy, acupuncture, acupressure, massage, chiropractic, craniosacral therapy, biofeedback, yoga and meditation.