Drug interactions

Q I regularly take aspirin but, recently, I’ve been prescribed an antihypertensive. Is there any interaction between these drugs? – CH, Swindon


A The effect of one drug on another is almost never tested when it’s first licensed, so any reactions are noticed only when patients complain of side-effects.


Antihypertensives tend to be ‘lifestyle’ drugs, and are often prescribed for long periods of time. As a result, they are often taken with other drugs, and there’s a long list of drugs with which they can adversely react – aspirin is among them.


Drug interaction is more common, and more serious, in the elderly. Such patients are more likely to be taking a huge cocktail of various drugs – called ‘polypharmacy’ – and their kidneys are less able to cope with the toxic load.


Antihypertensives can interact with beta-blockers, diuretics, ACE inhibitors, NSAIDs (non-steroidal anti-inflammatory drugs) such as aspirin, and other antihypertensives. High-dose (but not low-dose) aspirin can negate the effects of your antihypertensive (J Hypertens, 2002; 20: 1015-22).

What Doctors Don't Tell You Written by What Doctors Don't Tell You

We Humbly Recommend

Get the Healthiest Newsletter!

Get a dose of Healthy delivered straight to your inbox. Each FREE issue features amazing content that will elevate your Body, Mind, and Spirit.

Your data is never shared with 3rd parties

Introducing

Healthy Shopping

Health and Wellbeing products lovingly curated for you.