Researchers fear that even the granddaughters of DES (diethylstilbestrol) mothers could be at increased risk of developing cancer.
It’s been established that daughters of DES mothers are more likely to develop a reproductive tract cancer, but the cascade effect through the generations is something new and alarming.
The discovery has been made by researchers from the National Institute of Environmental Health Sciences after carrying out experiments on mice.
Women who were at greater risk of miscarriage took DES, a synthetic estrogen, for more than 20 years until 1971 when the first cases of cancer in the daughters were reported (Carcinogenesis, 1998; 19: 1655-63).